Detalhe da pesquisa
1.
LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.
Cell
; 186(26): 5766-5783.e25, 2023 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134874
2.
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Nat Immunol
; 23(6): 878-891, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618831
3.
KIF2A deficiency causes early-onset neurodegeneration.
Proc Natl Acad Sci U S A
; 119(46): e2209714119, 2022 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343267
4.
An immunological puzzle: The adaptive immune system fuels Alzheimer's disease pathology.
Brain Behav Immun
; 117: 122-134, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38142916
5.
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy.
Brain
; 145(12): 4368-4384, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36039535
6.
SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function.
PLoS Biol
; 17(10): e3000466, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31658245
7.
Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25.
J Neurosci
; 37(17): 4525-4539, 2017 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348137
8.
Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.
Alzheimers Dement
; 14(10): 1261-1280, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30036493
9.
Interactions Between SNAP-25 and Synaptotagmin-1 Are Involved in Vesicle Priming, Clamping Spontaneous and Stimulating Evoked Neurotransmission.
J Neurosci
; 36(47): 11865-11880, 2016 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27881774
10.
Innervation by a GABAergic neuron depresses spontaneous release in glutamatergic neurons and unveils the clamping phenotype of synaptotagmin-1.
J Neurosci
; 34(6): 2100-10, 2014 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24501351
11.
Spatially Self-Organized Three-Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development.
Adv Sci (Weinh)
; 11(5): e2304421, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38037510
12.
Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites.
Dev Cell
; 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38626765
13.
Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling.
J Extracell Vesicles
; 12(2): e12306, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792546
14.
A facile method to generate cerebral organoids from human pluripotent stem cells.
EXCLI J
; 22: 1055-1076, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37927348
15.
Mitochondria metabolism sets the species-specific tempo of neuronal development.
Science
; 379(6632): eabn4705, 2023 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36705539
16.
Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.
Nat Neurosci
; 26(6): 1021-1031, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188873
17.
AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model.
EMBO Mol Med
; 14(4): e09824, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35352880
18.
Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity.
Neuron
; 54(2): 275-90, 2007 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17442248
19.
Corticotropin-releasing factor induces functional and structural synaptic remodelling in acute stress.
Transl Psychiatry
; 11(1): 378, 2021 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34234103
20.
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation.
Neuron
; 109(5): 767-777.e5, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472038